Select Save as type PDF. 6. Check Open All Documents with this type. How Do I Stop Adobe Reader From Opening When a PDF is Saved 1. Open Chrome Settings. 1. Scroll to the bottom and click Advanced. 2. Under the Downloads heading (under the Documents column), click Clear next to save PDF file while downloading” Click Save All PDF files. 2. Open Chrome. 3. Open the URL of the file 4. Click Open. Click Save PDF. 5. Open another PDF or text document with Adobe Reader. 6. It will open Adobe Reader. 5. Remove the checkbox labelled open a certain file type of file after.... 6. Open All Documents with this type. 4. Click on the three (vertical) dots in the upper right corner of the Chrome browser window. Select Settings. 3. Under the General icon, click Save as type: PDF. 4.